Some years ago, I remember reading a post by someone who mentioned he has an actual diagnosis of Asperger's syndrome. Based on what I've seen, I think that several other posters also have that syndrome but maybe don't realize it. From Asperger's, there are certain behavioral symptoms that would make normal people shun them and alienate them. So no matter how hard they try, they would be Unable to socialize successfully. That is, until they receive proper therapy. I don't know whether Asperger's can be treated by meds or not, but certainly that area should be explored.